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LETM1-Mediated K(+) and Na(+) Homeostasis Regulates Mitochondrial Ca(2+) Efflux

Ca(2+) transport across the inner membrane of mitochondria (IMM) is of major importance for their functions in bioenergetics, cell death and signaling. It is therefore tightly regulated. It has been recently proposed that LETM1—an IMM protein with a crucial role in mitochondrial K(+)/H(+) exchange a...

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Detalles Bibliográficos
Autores principales: Austin, Shane, Tavakoli, Mojtaba, Pfeiffer, Christina, Seifert, Julia, Mattarei, Andrea, De Stefani, Diego, Zoratti, Mario, Nowikovsky, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698270/
https://www.ncbi.nlm.nih.gov/pubmed/29204122
http://dx.doi.org/10.3389/fphys.2017.00839