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Helicobacter pylori targets mitochondrial import and components of mitochondrial DNA replication machinery through an alternative VacA-dependent and a VacA-independent mechanisms

Targeting mitochondria is a powerful strategy for pathogens to subvert cell physiology and establish infection. Helicobacter pylori is a bacterial pathogen associated with gastric cancer development that is known to target mitochondria directly and exclusively through its pro-apoptotic and vacuolati...

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Detalles Bibliográficos
Autores principales: Chatre, Laurent, Fernandes, Julien, Michel, Valérie, Fiette, Laurence, Avé, Patrick, Arena, Giuseppe, Jain, Utkarsh, Haas, Rainer, Wang, Timothy C., Ricchetti, Miria, Touati, Eliette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698309/
https://www.ncbi.nlm.nih.gov/pubmed/29162845
http://dx.doi.org/10.1038/s41598-017-15567-3