A signal-amplifiable biochip quantifies extracellular vesicle-associated RNAs for early cancer detection

Detection of extracellular vesicle (EV)-associated RNAs with low expression levels in early-stage cancer remains a challenge and is highly valuable. Here, we report a nanoparticle-based biochip that could capture circulating EVs without isolation, brighten encapsulated RNAs, and amplify fluorescence...

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Detalles Bibliográficos
Autores principales: Hu, Jiaming, Sheng, Yan, Kwak, Kwang Joo, Shi, Junfeng, Yu, Bohao, Lee, L. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698315/
https://www.ncbi.nlm.nih.gov/pubmed/29162835
http://dx.doi.org/10.1038/s41467-017-01942-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698315/
https://www.ncbi.nlm.nih.gov/pubmed/29162835
http://dx.doi.org/10.1038/s41467-017-01942-1

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