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A signal-amplifiable biochip quantifies extracellular vesicle-associated RNAs for early cancer detection
Detection of extracellular vesicle (EV)-associated RNAs with low expression levels in early-stage cancer remains a challenge and is highly valuable. Here, we report a nanoparticle-based biochip that could capture circulating EVs without isolation, brighten encapsulated RNAs, and amplify fluorescence...
Autores principales: | Hu, Jiaming, Sheng, Yan, Kwak, Kwang Joo, Shi, Junfeng, Yu, Bohao, Lee, L. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698315/ https://www.ncbi.nlm.nih.gov/pubmed/29162835 http://dx.doi.org/10.1038/s41467-017-01942-1 |
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