Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes

The microtubule-associated protein Tau plays a central role in the pathogenesis of Alzheimer’s disease. Although Tau interaction with membranes is thought to affect some of its physiological functions and its aggregation properties, the sequence determinants and the structural and functional consequ...

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Detalles Bibliográficos
Autores principales: Ait-Bouziad, Nadine, Lv, Guohua, Mahul-Mellier, Anne-Laure, Xiao, Shifeng, Zorludemir, Gizem, Eliezer, David, Walz, Thomas, Lashuel, Hilal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698329/
https://www.ncbi.nlm.nih.gov/pubmed/29162800
http://dx.doi.org/10.1038/s41467-017-01575-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698329/
https://www.ncbi.nlm.nih.gov/pubmed/29162800
http://dx.doi.org/10.1038/s41467-017-01575-4

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