Hypoxia induces epithelial-mesenchymal transition in colorectal cancer cells through ubiquitin-specific protease 47-mediated stabilization of Snail: A potential role of Sox9

During the metastatic phase, cancer cells require the dissolution of cadherin-mediated cell-cell adhesion and a dramatic re-organization of the cytoskeleton through epithelial-mesenchymal transition (EMT), thereby acquiring migratory and invasive capabilities. In most tumors, EMT is accompanied by h...

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Detalles Bibliográficos
Autores principales: Choi, Bae-Jung, Park, Sin-Aye, Lee, Sung-Young, Cha, Young Nam, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698333/
https://www.ncbi.nlm.nih.gov/pubmed/29162839
http://dx.doi.org/10.1038/s41598-017-15139-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698333/
https://www.ncbi.nlm.nih.gov/pubmed/29162839
http://dx.doi.org/10.1038/s41598-017-15139-5

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