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Whey Protein Concentrate Renders MDA-MB-231 Cells Sensitive to Rapamycin by Altering Cellular Redox State and Activating GSK3β/mTOR Signaling

Whey protein concentrate (WPC) is an amino acid-rich supplement that has been shown to increase cellular antioxidant capacity. Mammalian target of rapamycin (mTOR) is a crucial regulator of signaling in mammalian cells, and serves as a therapeutic target for triple-negative breast cancer (TNBC). Thi...

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Detalles Bibliográficos
Autores principales: Cheng, Shih-Hsuan, Tseng, Yang-Ming, Wu, Szu-Hsien, Tsai, Shih-Meng, Tsai, Li-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698404/
https://www.ncbi.nlm.nih.gov/pubmed/29162840
http://dx.doi.org/10.1038/s41598-017-14159-5