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Whey Protein Concentrate Renders MDA-MB-231 Cells Sensitive to Rapamycin by Altering Cellular Redox State and Activating GSK3β/mTOR Signaling
Whey protein concentrate (WPC) is an amino acid-rich supplement that has been shown to increase cellular antioxidant capacity. Mammalian target of rapamycin (mTOR) is a crucial regulator of signaling in mammalian cells, and serves as a therapeutic target for triple-negative breast cancer (TNBC). Thi...
Autores principales: | Cheng, Shih-Hsuan, Tseng, Yang-Ming, Wu, Szu-Hsien, Tsai, Shih-Meng, Tsai, Li-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698404/ https://www.ncbi.nlm.nih.gov/pubmed/29162840 http://dx.doi.org/10.1038/s41598-017-14159-5 |
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