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Chemogenomic analysis reveals key role for lysine acetylation in regulating Arc stability

The role of Arc in synaptic plasticity and memory consolidation has been investigated for many years with recent evidence that defects in the expression or activity of this immediate-early gene may also contribute to the pathophysiology of brain disorders including schizophrenia and fragile X syndro...

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Detalles Bibliográficos
Autores principales: Lalonde, Jasmin, Reis, Surya A., Sivakumaran, Sudhir, Holland, Carl S., Wesseling, Hendrik, Sauld, John F., Alural, Begum, Zhao, Wen-Ning, Steen, Judith A., Haggarty, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698418/
https://www.ncbi.nlm.nih.gov/pubmed/29162813
http://dx.doi.org/10.1038/s41467-017-01750-7