3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry

The topographical organization of collagen within the tumor microenvironment has been implicated in modulating cancer cell migration and independently predicts progression to metastasis. Here, we show that collagen matrices with small pores and short fibers, but not Matrigel, trigger a conserved tra...

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Detalles Bibliográficos
Autores principales: Velez, D. O., Tsui, B., Goshia, T., Chute, C. L., Han, A., Carter, H., Fraley, S. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698427/
https://www.ncbi.nlm.nih.gov/pubmed/29162797
http://dx.doi.org/10.1038/s41467-017-01556-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698427/
https://www.ncbi.nlm.nih.gov/pubmed/29162797
http://dx.doi.org/10.1038/s41467-017-01556-7

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