TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity

STAT3 is a pleiotropic transcription factor involved in homeostatic and host defense processes in the human body. It is activated by numerous cytokines and growth factors and generates a series of cellular effects. Of the STAT-mediated signal transduction pathways, STAT3 transcriptional control is b...

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Detalles Bibliográficos
Autores principales: Mori, Raffaele, Wauman, Joris, Icardi, Laura, Van der Heyden, José, De Cauwer, Lode, Peelman, Frank, De Bosscher, Karolien, Tavernier, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698428/
https://www.ncbi.nlm.nih.gov/pubmed/29162862
http://dx.doi.org/10.1038/s41598-017-15912-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698428/
https://www.ncbi.nlm.nih.gov/pubmed/29162862
http://dx.doi.org/10.1038/s41598-017-15912-6

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