Molecular basis of AKAP79 regulation by calmodulin

AKAP79/150 is essential for coordinating second messenger-responsive enzymes in processes including synaptic long-term depression. Ca(2+) directly regulates AKAP79 through its effector calmodulin (CaM), but the molecular basis of this regulation was previously unknown. Here, we report that CaM recog...

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Detalles Bibliográficos
Autores principales: Patel, Neha, Stengel, Florian, Aebersold, Ruedi, Gold, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698441/
https://www.ncbi.nlm.nih.gov/pubmed/29162807
http://dx.doi.org/10.1038/s41467-017-01715-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698441/
https://www.ncbi.nlm.nih.gov/pubmed/29162807
http://dx.doi.org/10.1038/s41467-017-01715-w

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