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Molecular basis of AKAP79 regulation by calmodulin
AKAP79/150 is essential for coordinating second messenger-responsive enzymes in processes including synaptic long-term depression. Ca(2+) directly regulates AKAP79 through its effector calmodulin (CaM), but the molecular basis of this regulation was previously unknown. Here, we report that CaM recog...
Autores principales: | Patel, Neha, Stengel, Florian, Aebersold, Ruedi, Gold, Matthew G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698441/ https://www.ncbi.nlm.nih.gov/pubmed/29162807 http://dx.doi.org/10.1038/s41467-017-01715-w |
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