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β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents I(Ks) and I(Kr) in the human ventricle

Long QT syndrome (LQTS) is an inherited or drug induced condition associated with delayed repolarization and sudden cardiac death. The cardiac potassium channel, I(Kr), and the adrenergic-sensitive cardiac potassium current, I(Ks), are two primary contributors to cardiac repolarization. This study a...

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Detalles Bibliográficos
Autores principales: Kang, C., Badiceanu, A., Brennan, J. A., Gloschat, C., Qiao, Y., Trayanova, N. A., Efimov, I. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698468/
https://www.ncbi.nlm.nih.gov/pubmed/29162896
http://dx.doi.org/10.1038/s41598-017-16218-3