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β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents I(Ks) and I(Kr) in the human ventricle
Long QT syndrome (LQTS) is an inherited or drug induced condition associated with delayed repolarization and sudden cardiac death. The cardiac potassium channel, I(Kr), and the adrenergic-sensitive cardiac potassium current, I(Ks), are two primary contributors to cardiac repolarization. This study a...
Autores principales: | Kang, C., Badiceanu, A., Brennan, J. A., Gloschat, C., Qiao, Y., Trayanova, N. A., Efimov, I. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698468/ https://www.ncbi.nlm.nih.gov/pubmed/29162896 http://dx.doi.org/10.1038/s41598-017-16218-3 |
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