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IGF-1-mediated PKM2/β-catenin/miR-152 regulatory circuit in breast cancer

Dysregulation of miRNAs is important in breast cancer initiation and malignant progression. Recently we showed that miR-152 downregulation is associated with breast cancer development, yet the underlying mechanism of miR-152 remains to be well elucidated. In this study, we identified β-catenin as a...

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Detalles Bibliográficos
Autores principales: Wen, Yi-Yang, Liu, Wei-Tao, Sun, Hao-Ran, Ge, Xin, Shi, Zhu-Mei, Wang, Min, Li, Wei, Zhang, Jian-Ying, Liu, Ling-Zhi, Jiang, Bing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698474/
https://www.ncbi.nlm.nih.gov/pubmed/29162853
http://dx.doi.org/10.1038/s41598-017-15607-y