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AFM-based detection of glycocalyx degradation and endothelial stiffening in the db/db mouse model of diabetes

Degradation of the glycocalyx and stiffening of endothelium are important pathophysiological components of endothelial dysfunction. However, to our knowledge, these events have not been investigated in tandem in experimental diabetes. Here, the mechanical properties of the glycocalyx and endothelium...

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Detalles Bibliográficos
Autores principales: Targosz-Korecka, Marta, Jaglarz, Magdalena, Malek-Zietek, Katarzyna E., Gregorius, Aleksandra, Zakrzewska, Agnieszka, Sitek, Barbara, Rajfur, Zenon, Chlopicki, Stefan, Szymonski, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698475/
https://www.ncbi.nlm.nih.gov/pubmed/29162916
http://dx.doi.org/10.1038/s41598-017-16179-7