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AFM-based detection of glycocalyx degradation and endothelial stiffening in the db/db mouse model of diabetes
Degradation of the glycocalyx and stiffening of endothelium are important pathophysiological components of endothelial dysfunction. However, to our knowledge, these events have not been investigated in tandem in experimental diabetes. Here, the mechanical properties of the glycocalyx and endothelium...
Autores principales: | Targosz-Korecka, Marta, Jaglarz, Magdalena, Malek-Zietek, Katarzyna E., Gregorius, Aleksandra, Zakrzewska, Agnieszka, Sitek, Barbara, Rajfur, Zenon, Chlopicki, Stefan, Szymonski, Marek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698475/ https://www.ncbi.nlm.nih.gov/pubmed/29162916 http://dx.doi.org/10.1038/s41598-017-16179-7 |
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