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Discrete False-Discovery Rate Improves Identification of Differentially Abundant Microbes

Differential abundance testing is a critical task in microbiome studies that is complicated by the sparsity of data matrices. Here we adapt for microbiome studies a solution from the field of gene expression analysis to produce a new method, discrete false-discovery rate (DS-FDR), that greatly impro...

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Detalles Bibliográficos
Autores principales: Jiang, Lingjing, Amir, Amnon, Morton, James T., Heller, Ruth, Arias-Castro, Ery, Knight, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698492/
https://www.ncbi.nlm.nih.gov/pubmed/29181446
http://dx.doi.org/10.1128/mSystems.00092-17