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Discrete False-Discovery Rate Improves Identification of Differentially Abundant Microbes
Differential abundance testing is a critical task in microbiome studies that is complicated by the sparsity of data matrices. Here we adapt for microbiome studies a solution from the field of gene expression analysis to produce a new method, discrete false-discovery rate (DS-FDR), that greatly impro...
Autores principales: | Jiang, Lingjing, Amir, Amnon, Morton, James T., Heller, Ruth, Arias-Castro, Ery, Knight, Rob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698492/ https://www.ncbi.nlm.nih.gov/pubmed/29181446 http://dx.doi.org/10.1128/mSystems.00092-17 |
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