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Novel p53 therapies for head and neck cancer

Inactivation of the tumor suppressor p53 is the predominant pathogenetic event in head and neck squamous cell carcinoma (HNSCC). The p53 pathway in HNSCC can be compromised through multiple mechanisms including gene mutations, hyperactivation of endogenous negative p53 regulators and by the human pa...

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Detalles Bibliográficos
Autores principales: Castellanos, Mario R., Pan, Quintin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698513/
https://www.ncbi.nlm.nih.gov/pubmed/29204550
http://dx.doi.org/10.1016/j.wjorl.2016.05.005