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Persistence of an Oncogenic Papillomavirus Genome Requires cis Elements from the Viral Transcriptional Enhancer
Human papillomavirus (HPV) genomes are replicated and maintained as extrachromosomal plasmids during persistent infection. The viral E2 proteins are thought to promote stable maintenance replication by tethering the viral DNA to host chromatin. However, this has been very difficult to prove genetica...
Autores principales: | Van Doorslaer, Koenraad, Chen, Dan, Chapman, Sandra, Khan, Jameela, McBride, Alison A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698554/ https://www.ncbi.nlm.nih.gov/pubmed/29162712 http://dx.doi.org/10.1128/mBio.01758-17 |
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