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The acute effect of beta‐guanidinopropionic acid versus creatine or placebo in healthy men (ABC‐Trial): A randomized controlled first‐in‐human trial

AIMS: Increasing evidence indicates that the ATP‐generating enzyme creatine kinase (CK) is involved in hypertension. CK rapidly regenerates ATP from creatine phosphate and ADP. Recently, it has been shown that beta‐guanidinopropionic acid (GPA), a kidney‐synthesized creatine analogue and competitive...

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Detalles Bibliográficos
Autores principales: Karamat, Fares A., Horjus, Deborah L., Haan, Yentl C., van der Woude, Lisa, Schaap, Marianne C., Oudman, Inge, van Montfrans, Gert A., Nieuwland, Rienk, Salomons, Gajja S., Clark, Joseph F., Brewster, Lizzy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698587/
https://www.ncbi.nlm.nih.gov/pubmed/28795416
http://dx.doi.org/10.1111/bcp.13390