Single‐dose pharmacokinetics of co‐crystal of tramadol–celecoxib: Results of a four‐way randomized open‐label phase I clinical trial in healthy subjects

AIMS: Co‐crystal of tramadol–celecoxib (CTC) is a novel co‐crystal molecule containing two active pharmaceutical ingredients under development by Esteve (E‐58425) and Mundipharma Research (MR308). This Phase I study compared single‐dose pharmacokinetics (PK) of CTC with those of the individual refer...

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Detalles Bibliográficos
Autores principales: Videla, Sebastián, Lahjou, Mounia, Vaqué, Anna, Sust, Mariano, Encabo, Mercedes, Soler, Lluis, Sans, Artur, Sicard, Eric, Gascón, Neus, Encina, Gregorio, Plata‐Salamán, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Pharmacokinetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698592/
https://www.ncbi.nlm.nih.gov/pubmed/28810061
http://dx.doi.org/10.1111/bcp.13395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698592/
https://www.ncbi.nlm.nih.gov/pubmed/28810061
http://dx.doi.org/10.1111/bcp.13395

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