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Background selection as null hypothesis in population genomics: insights and challenges from Drosophila studies
The consequences of selection at linked sites are multiple and widespread across the genomes of most species. Here, I first review the main concepts behind models of selection and linkage in recombining genomes, present the difficulty in parametrizing these models simply as a reduction in effective...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Royal Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698629/ https://www.ncbi.nlm.nih.gov/pubmed/29109230 http://dx.doi.org/10.1098/rstb.2016.0471 |