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Background selection as null hypothesis in population genomics: insights and challenges from Drosophila studies

The consequences of selection at linked sites are multiple and widespread across the genomes of most species. Here, I first review the main concepts behind models of selection and linkage in recombining genomes, present the difficulty in parametrizing these models simply as a reduction in effective...

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Detalles Bibliográficos
Autor principal: Comeron, Josep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698629/
https://www.ncbi.nlm.nih.gov/pubmed/29109230
http://dx.doi.org/10.1098/rstb.2016.0471