Comparing BMD‐derived genotoxic potency estimations across variants of the transgenic rodent gene mutation assay

There is growing interest in quantitative analysis of in vivo genetic toxicity dose‐response data, and use of point‐of‐departure (PoD) metrics such as the benchmark dose (BMD) for human health risk assessment (HHRA). Currently, multiple transgenic rodent (TGR) assay variants, employing different rod...

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Detalles Bibliográficos
Autores principales: Wills, John W., Johnson, George E., Battaion, Hannah L., Slob, Wout, White, Paul A., Gollapudi, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698699/
https://www.ncbi.nlm.nih.gov/pubmed/28945287
http://dx.doi.org/10.1002/em.22137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698699/
https://www.ncbi.nlm.nih.gov/pubmed/28945287
http://dx.doi.org/10.1002/em.22137

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