Hypothesis – buttressed rings assemble, clamp, and release SNAREpins for synaptic transmission

Neural networks are optimized to detect temporal coincidence on the millisecond timescale. Here, we offer a synthetic hypothesis based on recent structural insights into SNAREs and the C2 domain proteins to explain how synaptic transmission can keep this pace. We suggest that an outer ring of up to...

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Detalles Bibliográficos
Autores principales: Rothman, James E., Krishnakumar, Shyam S., Grushin, Kirill, Pincet, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698743/
https://www.ncbi.nlm.nih.gov/pubmed/28983915
http://dx.doi.org/10.1002/1873-3468.12874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698743/
https://www.ncbi.nlm.nih.gov/pubmed/28983915
http://dx.doi.org/10.1002/1873-3468.12874

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