Biosynthesis of the Enterotoxic Pyrrolobenzodiazepine Natural Product Tilivalline

The nonribosomal enterotoxin tilivalline was the first naturally occurring pyrrolobenzodiazepine to be linked to disease in the human intestine. Since the producing organism Klebsiella oxytoca is part of the intestinal microbiota and the pyrrolobenzodiazepine causes the pathogenesis of colitis it is...

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Detalles Bibliográficos
Autores principales: Dornisch, Elisabeth, Pletz, Jakob, Glabonjat, Ronald A., Martin, Florian, Lembacher‐Fadum, Christian, Neger, Margit, Högenauer, Christoph, Francesconi, Kevin, Kroutil, Wolfgang, Zangger, Klaus, Breinbauer, Rolf, Zechner, Ellen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698749/
https://www.ncbi.nlm.nih.gov/pubmed/28977734
http://dx.doi.org/10.1002/anie.201707737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698749/
https://www.ncbi.nlm.nih.gov/pubmed/28977734
http://dx.doi.org/10.1002/anie.201707737

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