Efficacy and Mechanism of Preoperative Simvastatin Therapy on Myocardial Protection after Extracorporeal Circulation

BACKGROUND: Cardiopulmonary bypass (CPB) causes systemic inflammatory response and ischemia-reperfusion (IR) injury. OBJECTIVE: To investigate the effect and mechanism of simvastatin on myocardial injury in cardiac valve surgery with CPB. METHODS: One hundred thirty patients were randomly assigned t...

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Detalles Bibliográficos
Autores principales: Hua, Ping, Liu, Jianyang, Tao, Jun, Zou, Rongjun, Lin, Xifeng, Zhang, Dingwen, Yang, Songran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698794/
https://www.ncbi.nlm.nih.gov/pubmed/29250545
http://dx.doi.org/10.1155/2017/6082430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698794/
https://www.ncbi.nlm.nih.gov/pubmed/29250545
http://dx.doi.org/10.1155/2017/6082430

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