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Efficacy and Mechanism of Preoperative Simvastatin Therapy on Myocardial Protection after Extracorporeal Circulation

BACKGROUND: Cardiopulmonary bypass (CPB) causes systemic inflammatory response and ischemia-reperfusion (IR) injury. OBJECTIVE: To investigate the effect and mechanism of simvastatin on myocardial injury in cardiac valve surgery with CPB. METHODS: One hundred thirty patients were randomly assigned t...

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Detalles Bibliográficos
Autores principales:	Hua, Ping, Liu, Jianyang, Tao, Jun, Zou, Rongjun, Lin, Xifeng, Zhang, Dingwen, Yang, Songran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698794/ https://www.ncbi.nlm.nih.gov/pubmed/29250545 http://dx.doi.org/10.1155/2017/6082430

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