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Transcriptome profiling of aging Drosophila photoreceptors reveals gene expression trends that correlate with visual senescence

BACKGROUND: Aging is associated with functional decline of neurons and increased incidence of both neurodegenerative and ocular disease. Photoreceptor neurons in Drosophila melanogaster provide a powerful model for studying the molecular changes involved in functional senescence of neurons since dec...

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Detalles Bibliográficos
Autores principales: Hall, Hana, Medina, Patrick, Cooper, Daphne A., Escobedo, Spencer E., Rounds, Jeremiah, Brennan, Kaelan J., Vincent, Christopher, Miura, Pedro, Doerge, Rebecca, Weake, Vikki M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698953/
https://www.ncbi.nlm.nih.gov/pubmed/29162050
http://dx.doi.org/10.1186/s12864-017-4304-3