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Active site voltage clamp fluorometry of the sodium glucose cotransporter hSGLT1
In the human sodium glucose cotransporter (hSGLT1) cycle, the protein undergoes conformational changes where the sugar-binding site alternatively faces the external and internal surfaces. Functional site-directed fluorometry was used to probe the conformational changes at the sugar-binding site. Res...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699082/ https://www.ncbi.nlm.nih.gov/pubmed/29087341 http://dx.doi.org/10.1073/pnas.1713899114 |