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Active site voltage clamp fluorometry of the sodium glucose cotransporter hSGLT1

In the human sodium glucose cotransporter (hSGLT1) cycle, the protein undergoes conformational changes where the sugar-binding site alternatively faces the external and internal surfaces. Functional site-directed fluorometry was used to probe the conformational changes at the sugar-binding site. Res...

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Detalles Bibliográficos
Autores principales: Gorraitz, Edurne, Hirayama, Bruce A., Paz, Aviv, Wright, Ernest M., Loo, Donald D. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699082/
https://www.ncbi.nlm.nih.gov/pubmed/29087341
http://dx.doi.org/10.1073/pnas.1713899114