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The margin of internal exposure (MOIE) concept for dermal risk assessment based on oral toxicity data – A case study with caffeine
Route-to-route extrapolation is a common part of human risk assessment. Data from oral animal toxicity studies are commonly used to assess the safety of various but specific human dermal exposure scenarios. Using theoretical examples of various user scenarios, it was concluded that delineation of a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699174/ https://www.ncbi.nlm.nih.gov/pubmed/28288858 http://dx.doi.org/10.1016/j.tox.2017.03.012 |