Smyd1C Mediates CD8 T Cell Death via Regulation of Bcl2-Mediated Restriction of outer Mitochondrial Membrane Integrity

The SET and Mynd domain 1 (Smyd1) locus encodes three tissue-restricted isoforms. Two previously characterized isoforms, Smyd1A and Smyd1B, are heart and skeletal muscle-restricted histone methyl transferases. Here we report that a third, non-catalytic isoform, Smyd1C, is expressed predominantly in...

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Detalles Bibliográficos
Autores principales: Nie, Hui, Rathbun, Gary, Tucker, Haley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699232/
https://www.ncbi.nlm.nih.gov/pubmed/29177249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699232/
https://www.ncbi.nlm.nih.gov/pubmed/29177249

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