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Deazaguanine derivatives, examples of crosstalk between RNA and DNA modification pathways

Seven-deazapurine modifications were thought to be highly specific of tRNAs, but have now been discovered in DNA of phages and of phylogenetically diverse bacteria, illustrating the plasticity of these modification pathways. The intermediate 7-cyano-7-deazaguanine (preQ(0)) is a shared precursor in...

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Detalles Bibliográficos
Autores principales: Hutinet, Geoffrey, Swarjo, Manal A., de Crécy-Lagard, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699537/
https://www.ncbi.nlm.nih.gov/pubmed/27937735
http://dx.doi.org/10.1080/15476286.2016.1265200