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Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

rRNAs are extensively modified during their transcription and subsequent maturation in the nucleolus, nucleus and cytoplasm. RNA modifications, which are installed either by snoRNA-guided or by stand-alone enzymes, generally stabilize the structure of the ribosome. However, they also cluster at func...

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Detalles Bibliográficos
Autores principales: Sloan, Katherine E., Warda, Ahmed S., Sharma, Sunny, Entian, Karl-Dieter, Lafontaine, Denis L. J., Bohnsack, Markus T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699541/
https://www.ncbi.nlm.nih.gov/pubmed/27911188
http://dx.doi.org/10.1080/15476286.2016.1259781