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The RNA methyltransferase Dnmt2 methylates DNA in the structural context of a tRNA

The amino acid sequence of Dnmt2 is very similar to the catalytic domains of bacterial and eukaryotic DNA-(cytosine 5)-methyltransferases, but it efficiently catalyzes tRNA methylation, while its DNA methyltransferase activity is the subject of controversial reports with rates varying between zero a...

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Detalles Bibliográficos
Autores principales: Kaiser, Steffen, Jurkowski, Tomasz P., Kellner, Stefanie, Schneider, Dirk, Jeltsch, Albert, Helm, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699543/
https://www.ncbi.nlm.nih.gov/pubmed/27819523
http://dx.doi.org/10.1080/15476286.2016.1236170