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Predicting tacrolimus concentrations in children receiving a heart transplant using a population pharmacokinetic model

OBJECTIVE: Immunosuppressant therapy plays a pivotal role in transplant success and longevity. Tacrolimus, a primary immunosuppressive agent, is well known to exhibit significant pharmacological interpatient and intrapatient variability. This variability necessitates the collection of serial trough...

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Detalles Bibliográficos
Autores principales: Rower, Joseph E, Stockmann, Chris, Linakis, Matthew W, Kumar, Shaun S, Liu, Xiaoxi, Korgenski, E Kent, Sherwin, Catherine M T, Molina, Kimberly M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699789/
https://www.ncbi.nlm.nih.gov/pubmed/29177199
http://dx.doi.org/10.1136/bmjpo-2017-000147