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Comprehensive molecular profiling of 718 Multiple Myelomas reveals significant differences in mutation frequencies between African and European descent cases

Multiple Myeloma (MM) is a plasma cell malignancy with significantly greater incidence and mortality rates among African Americans (AA) compared to Caucasians (CA). The overall goal of this study is to elucidate differences in molecular alterations in MM as a function of self-reported race and genet...

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Detalles Bibliográficos
Autores principales: Manojlovic, Zarko, Christofferson, Austin, Liang, Winnie S., Aldrich, Jessica, Washington, Megan, Wong, Shukmei, Rohrer, Daniel, Jewell, Scott, Kittles, Rick A., Derome, Mary, Auclair, Daniel, Craig, David Wesley, Keats, Jonathan, Carpten, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699827/
https://www.ncbi.nlm.nih.gov/pubmed/29166413
http://dx.doi.org/10.1371/journal.pgen.1007087