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Stiffness analysis of 3D spheroids using microtweezers

We describe a novel mechanical characterization method that has directly measured the stiffness of cancer spheroids for the first time to our knowledge. Stiffness is known to be a key parameter that characterizes cancerous and normal cells. Atomic force microscopy or optical tweezers have been typic...

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Detalles Bibliográficos
Autores principales: Jaiswal, Devina, Cowley, Norah, Bian, Zichao, Zheng, Guoan, Claffey, Kevin P., Hoshino, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699838/
https://www.ncbi.nlm.nih.gov/pubmed/29166651
http://dx.doi.org/10.1371/journal.pone.0188346