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Is there a reasonable excuse for not providing post-operative analgesia when using animal models of peripheral neuropathic pain for research purposes?

INTRODUCTION: The induction of neuropathic pain-like behaviors in rodents often requires surgical intervention. This engages acute nociceptive signaling events that contribute to pain and stress post-operatively that from a welfare perspective demands peri-operative analgesic treatment. However, a l...

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Detalles Bibliográficos
Autores principales: Hestehave, Sara, Munro, Gordon, Christensen, Rie, Brønnum Pedersen, Tina, Arvastson, Lars, Hougaard, Philip, Abelson, Klas S. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699849/
https://www.ncbi.nlm.nih.gov/pubmed/29166664
http://dx.doi.org/10.1371/journal.pone.0188113