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Is there a reasonable excuse for not providing post-operative analgesia when using animal models of peripheral neuropathic pain for research purposes?
INTRODUCTION: The induction of neuropathic pain-like behaviors in rodents often requires surgical intervention. This engages acute nociceptive signaling events that contribute to pain and stress post-operatively that from a welfare perspective demands peri-operative analgesic treatment. However, a l...
Autores principales: | Hestehave, Sara, Munro, Gordon, Christensen, Rie, Brønnum Pedersen, Tina, Arvastson, Lars, Hougaard, Philip, Abelson, Klas S. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699849/ https://www.ncbi.nlm.nih.gov/pubmed/29166664 http://dx.doi.org/10.1371/journal.pone.0188113 |
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