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Regulatory network structure determines patterns of intermolecular epistasis
Most phenotypes are determined by molecular systems composed of specifically interacting molecules. However, unlike for individual components, little is known about the distributions of mutational effects of molecular systems as a whole. We ask how the distribution of mutational effects of a transcr...
Autores principales: | Lagator, Mato, Sarikas, Srdjan, Acar, Hande, Bollback, Jonathan P, Guet, Călin C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699867/ https://www.ncbi.nlm.nih.gov/pubmed/29130883 http://dx.doi.org/10.7554/eLife.28921 |
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