Cargando…
Induction of fibroblast growth factor 21 does not require activation of the hepatic X-box binding protein 1 in mice
OBJECTIVE: Fibroblast growth factor 21 (FGF21), a key regulator of the metabolic response to fasting, is highly induced by endoplasmic reticulum (ER) stress. The X-box binding protein 1 (Xbp1) is one of several ER stress proteins that has been shown to directly activate the FGF21 promoter. We aimed...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699917/ https://www.ncbi.nlm.nih.gov/pubmed/29157602 http://dx.doi.org/10.1016/j.molmet.2017.09.006 |