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Induction of fibroblast growth factor 21 does not require activation of the hepatic X-box binding protein 1 in mice

OBJECTIVE: Fibroblast growth factor 21 (FGF21), a key regulator of the metabolic response to fasting, is highly induced by endoplasmic reticulum (ER) stress. The X-box binding protein 1 (Xbp1) is one of several ER stress proteins that has been shown to directly activate the FGF21 promoter. We aimed...

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Detalles Bibliográficos
Autores principales:	Olivares, Shantel, Henkel, Anne S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699917/ https://www.ncbi.nlm.nih.gov/pubmed/29157602 http://dx.doi.org/10.1016/j.molmet.2017.09.006

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