Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1

The bacteria-derived clustered regularly interspaced short palindromic repeat (CRISPR)–Cas systems are powerful tools for genome engineering. Recently, in addition to Cas protein engineering, the improvement of guide RNAs are also performed, contributing to broadening the research area of CRISPR–Cas...

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Detalles Bibliográficos
Autores principales: Kweon, Jiyeon, Jang, An-Hee, Kim, Da-eun, Yang, Jin Wook, Yoon, Mijung, Rim Shin, Ha, Kim, Jin-Soo, Kim, Yongsub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700056/
https://www.ncbi.nlm.nih.gov/pubmed/29167440
http://dx.doi.org/10.1038/s41467-017-01650-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700056/
https://www.ncbi.nlm.nih.gov/pubmed/29167440
http://dx.doi.org/10.1038/s41467-017-01650-w

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