Encapsulation of primary dopaminergic neurons in a GDNF-loaded collagen hydrogel increases their survival, re-innervation and function after intra-striatal transplantation

Poor graft survival limits the use of primary dopaminergic neurons for neural repair in Parkinson’s disease. Injectable hydrogels have the potential to significantly improve the outcome of such reparative approaches by providing a physical matrix for cell encapsulation which can be further enriched...

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Detalles Bibliográficos
Autores principales: Moriarty, Niamh, Pandit, Abhay, Dowd, Eilís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700093/
https://www.ncbi.nlm.nih.gov/pubmed/29167483
http://dx.doi.org/10.1038/s41598-017-15970-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700093/
https://www.ncbi.nlm.nih.gov/pubmed/29167483
http://dx.doi.org/10.1038/s41598-017-15970-w

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