Cargando…
Coupling of Polo kinase activation to nuclear localization by a bifunctional NLS is required during mitotic entry
The Polo kinase is a master regulator of mitosis and cytokinesis conserved from yeasts to humans. Polo is composed of an N-term kinase domain (KD) and a C-term polo-box domain (PBD), which regulates its subcellular localizations. The PBD and KD can interact and inhibit each other, and this reciproca...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700101/ https://www.ncbi.nlm.nih.gov/pubmed/29167465 http://dx.doi.org/10.1038/s41467-017-01876-8 |