Cargando…

Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster

DNA replication depends on primase, the specialised polymerase responsible for synthesis of the RNA primers that are elongated by the replicative DNA polymerases. In eukaryotic and archaeal replication, primase is a heterodimer of two subunits, PriS and PriL. Recently, a third primase subunit named...

Descripción completa

Detalles Bibliográficos
Autores principales: Holzer, Sandro, Yan, Jiangyu, Kilkenny, Mairi L., Bell, Stephen D., Pellegrini, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700102/
https://www.ncbi.nlm.nih.gov/pubmed/29167441
http://dx.doi.org/10.1038/s41467-017-01707-w