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Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster
DNA replication depends on primase, the specialised polymerase responsible for synthesis of the RNA primers that are elongated by the replicative DNA polymerases. In eukaryotic and archaeal replication, primase is a heterodimer of two subunits, PriS and PriL. Recently, a third primase subunit named...
Autores principales: | Holzer, Sandro, Yan, Jiangyu, Kilkenny, Mairi L., Bell, Stephen D., Pellegrini, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700102/ https://www.ncbi.nlm.nih.gov/pubmed/29167441 http://dx.doi.org/10.1038/s41467-017-01707-w |
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